The purpose of this experiment is to investigate the composition of compounds in Panacetin. Generally, it is made up of sucrose, aspirin and an unknown component, either acetanilide or phenacetin. SinceBy using different techniques, such as filtration, extraction, and evaporation, those three components have been isolated out, which is based on varies solubility and acid-based properties. The percentage of composition of Panacetin are also found, which is based on the mass of three dried components.
“panacetin” + Dichloromethane Solid sucrose + aspirin + unknown component (By Filtration) Aspirin + unknown components + NaOH aqueous layer + organic layer Aqueous layer + HCl aspirin (By filtration)
Organic layer Unknown (By Evaporation)
Procedure and Observation:
0.30093 g of panacetin was weighed and mixed well with 50 ml of dichloromethane. After stirring the solution thoroughly, some solid is formed (solid sucrose) and liquid. With using a preweighed filter paper to filter the mixture, and after the sucrose had dried, it was weighed out to 0.
7756g. For the aqueous layer, adding 10ml of 6M HCl(pH 2) and filtered using vacuum filtration and after cooled in the ice bath. Leaving behind is the solid aspirin which was weighed out as 1.2469g. Lastly, to measure the weight of the unknown solid component of panacetin, putting the organic layer in a warm water bath to evaporate the solvent and the remain is the solid residue.
Extract the unknown solid component of panacetin, which was weighed to be 0.8946g. After measure the unknown component, transferring the sample into the beaker with the hot water to dissolve the sample completely and then letting it cool by putting the beaker into the ice. After that, collect the solid by vacuum filtration and the filtered product was weighed 1.1759g In order to measure the melting point, put the sample into the test tube and put the tube into the machine to heat it up. This helps to melt the sample by putting the heat energy into the system. From the result, the sample starts melt at 72°C and completely melt at 84°C.
The theatrical mass percentage: sucrose 10%, aspirin 40%, unknown 50%. The theoretical melting point of acetanilide is 90 ̊C and the theoretical melting point of phenacetin is 110 ̊C The actual mass percentage:
Sucrose mass percentage: (2.1409-1.3663) / 3.0093*100% = 25.74% Aspirin mass percentage: (1.2469/3.0093)*100% = 41.43%
Unknown mass percentage: (1.1759/3.0093)*100% = 39.07%
Actual melting point: The melting point of the sample is 84 ̊C, so it is acetanilide.
The sum up of the actual mass of sucrose, aspirin and unknown mass sample is 3.1974g. The reason why the total mass is greater than the mass of the original mass, 3.0093g because the extra mass was gaining from the process of adding hot water to dissolve the product. It could also mean that my lab partner and I did not give sufficient time for the sample to recrystallize. There is difference melting point of acetanilide compared to its theoretical melting point. The reason is that the sample has a small melting point range. In my opinion, even though we have used mercury laboratory thermometer, since the sample has a small melting point range, in order to reduce the error made from reading the temperature, we should use more sensitive and accurate thermometer to find out the more “accurate” melting point of the sample. I would conclude that the melting point that our group found is 84 ̊C, which is close enough to the theoretical melting point.
It can be concluded that in 3.0093g of Panacetin, its composition is distributed as 25.74% of surcrose, 41.4% of Aspirin and 39.07% of acetanilide. The melting point of acetanilide is 84 ̊C, which is close enough to the theatrical melting point, 90 ̊C because acetanilide has a small melting point range.
Cite this essay
Experiment Separating the Components of “Panacetin”. (2017, Jan 09). Retrieved from https://studymoose.com/experiment-separating-the-components-of-panacetin-essay