Between 200 B. C. E. to 1450 C. E. the Silk Road’s interaction patterns changed with the Black Plague and the religious exchange between China and the West. However, the continuity was maintained with its main purpose of trading goods passed along its routes. Flea bites from rats would infect the Black Plague along merchants and consumers throughout Eurasia which caused a decline in the economy. During the Middle Ages ships would stop at various points such as Turkey, Lebanon, and Iraq that are along the Silk Road. People infected with the Black Plague would have bleeding under the skin, nervous system would collapse and eventually the deadly disease would lead to millions of death in both Asia and Europe….