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Peptide Essay Topics & Paper Examples

B-type natriuretic peptide

B-type natriuretic peptide or BNP is a neurohormone. It is secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes). Thus fluid overload increases the secretion of the hormone. BNP is elevated in those with left ventricular dysfunction. It is elevated in both symptomatic and asymptomatic left ventricular dysfunction. Whether BNP can be used as a test to diagnose congestive heart failure or CHF in early stages is a much debated topic. In many situations, BNP has been used as a screen for heart failure and to determine whether a patient has hypoxia secondary to CHF or pulmonary disease. Thus, BNP levels can help establish the cause of shortness of breath. This test…