AP Euro DBQ: Issues and Reactions due to the expansion of Manchester The process of industrialization in Manchester, England throughout the 19th century lead to the significant expansion of the city’s area and population, which caused environmental and health issues that were met with a protestation reaction. Although the industrial expansion spurred great economic growth in the city, it also lead to a great deterioration in the quality of life and the natural beauty of the city. The city’s expansion with industry led to the worsening of the environmental conditions in the city as pollutants from the industries reduced the quality and purity of the city. The expanding industrial city also increased human labor force exploitation as more and more laborers were being “used” to fulfill the ambitions of the factory owners. The people of the city reacted to these issues by protesting against the government for a change, disagreeing with these issues.