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Inhibition Essay Topics & Paper Examples

Feedback Inhibition

Feedback inhibition also known as end product inhibition refers to an important mechanism in the biosynthetic pathways involving enzymes. The synthesis of molecules such as amino acids and pyrimidines in the human body is tightly regulated and most of the steps controlled enzymatically. Usually, in feedback inhibition, the end products in biosynthetic pathways inhibit the first enzymatic step and hence controlling the synthesis of the end products themselves (Khanna, 289). The first enzyme in the pathway which is inhibited is known as the allosteric enzyme. This mechanism takes advantage of the preexisting enzymes already in the cells to control various biosynthetic processes. An interesting example of allosteric or feedback inhibition is what happens in the biosynthesis of pyrimidine nucleotide bases…